Targeting multiple cannabinoid anti-tumour pathways with a resorcinol derivative leads to inhibition of advanced stages of breast cancer

Autor:	Pranamee Sarma, Esther Martinez-Martinez, Ramesh Gujjar, Pierre-Yves Desprez, Mukkanti Amere, Jonathon Judkins, Eiman Elwakeel, Sean D. McAllister, Rumi Kawamura, Ryuichi Murase, Eric Singer, Anu Mahadevan, Sonali Dayal, Arash Pakdel
Rok vydání:	2014
Předmět:	Pharmacology organic chemicals medicine.medical_treatment digestive oral and skin physiology Advanced stage Cancer Biology medicine.disease Anti tumour Breast cancer mental disorders medicine lipids (amino acids peptides and proteins) Cannabinoid Cannabidiol medicine.drug Mice nude
Zdroj:	British Journal of Pharmacology. 171:4464-4477
ISSN:	0007-1188
DOI:	10.1111/bph.12803
Popis:	Background and Purpose The psychoactive cannabinoid Δ9-tetrahydrocannabinol (THC) and the non-psychoactive cannabinoid cannabidiol (CBD) can both reduce cancer progression, each through distinct anti-tumour pathways. Our goal was to discover a compound that could efficiently target both cannabinoid anti-tumour pathways.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e6b1f9246a3c4530b3996b260fa64efb https://doi.org/10.1111/bph.12803 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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