| Popis: |
A high incidence of mucosal lipomatosis at gastric cancer (GC) was detected at the absence of a correlation between body mass index and the severity of lipomatosis, which probably makes it possible to consider it as an independent phenomenon. Lipomatosis causes a statistically significant, compared to control, increase in mucosal thickness outside the tumor zone (morphometric analysis) in intestinal and diffuse types of GC, and in intestinal type of GC statistically significant differences in the thickness of the submucosa, subserous layers and the total thickness of the gastric mucosa in compared with diffuse type of gastric cancer. The significance of the phenomenon of mucosal lipomatosis in gastric cancer is not completely clear, but the known effects of adipose tissue (endocrine function, development of immune inflammation, etc.), association with myxomatous stromal degeneration and accumulation of transforming growth factor beta (TGF) do not exclude the influence of local adipose tissue deposits on carcinogenesis, which requires continue research |
