| Autor: |
T H Nielsen, H K Nielsen, Sofie Lindskov Hansen, N Fieldborg, Husegaard Hc, S E Husted |
| Rok vydání: |
1987 |
| Předmět: |
|
| Zdroj: |
XIth International Congress on Thrombosis and Haemostasis. |
| ISSN: |
2567-689X |
| DOI: |
10.1055/s-0038-1644888 |
| Popis: |
Postoperative frequency of deep venous thrombosis(DVT) is high, reported to be 13-59$ after abdominalsurgery and as high as 73$ after total hip replacement. Epidural anaesthesia can reduce the frequency ofDVT and pulmonary embolism. Platelet aggregation (PA) is supposed to play an important role in formationof DVT. In a randomized study twenty patients admitted to transarthroscopic meniscectomy were allocated to epidural or general anaesthesia. All operations were carried out in blood less field using a thigh tourniquet. S-cortisol, thromboxane-B2 (TxB2) and PAwere measured before premedication, before Itart of the operation and finally before and lo min after exsufflation of the tourniquet. Aggregability was measured in platelet -rich plasma and expressed as the treshold concentration of collagen and ADP. S-cortisol and TxB2 were measured by RIA. Collagen induced TxB2-synthesis in platelet-rich plasma was significanthigher during general as compared with epidural anaesthesia (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
