Claviform aspergillus-related vegetation in the left ventricle of a patient with systemic lupus erythematosus
| Autor: | Shimpei Kasagi, Chiyo Kurimoto, Jun Saegusa, Nobuhide Hayashi, Tetsushi Yamamoto, Akio Morinobu, Takamitsu Imanishi |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Voriconazole medicine.medical_specialty Aspergillus Combination therapy biology business.industry 030106 microbiology biology.organism_classification Disseminated aspergillosis Surgery 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Ventricle Aspergillus antigen Ascites medicine Radiology Nuclear Medicine and imaging medicine.symptom Vegetation (pathology) business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Journal of Clinical Ultrasound. 46:231-232 |
| ISSN: | 0091-2751 |
| DOI: | 10.1002/jcu.22501 |
| Popis: | A 38-year-old woman was diagnosed with systemic lupus erythematosus and received immunosuppressive therapy. After 6 months of treatment, workup for low-grade fever yielded elevated enzyme-linked immunosorbent assay titers for Aspergillus antigen in serum and ascites, leading to the diagnosis of disseminated aspergillosis. Transthoracic echocardiography revealed a claviform vegetation attached to the left ventricular anterior septum. Two days after the start of antifungal Amphotericin-B therapy, the patient suffered from several neurologic disorders. A second transthoracic echocardiography revealed that the vegetation decreased in size. Two weeks later, the vegetation increased again. Combination therapy of Amphotericin-B and Voriconazole was initiated, and the vegetation eventually disappeared completely. © 2017 Wiley Periodicals, Inc. J Clin Ultrasound 46:231-232, 2018. |
| Databáze: | OpenAIRE |
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