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In 1915 Sherrick 1 struck the death blow to luetin prepared from supposed cultures of Spirochaeta pallida by showing that nonsyphilitic patients who had been given iodides by mouth prior to, or following, the intradermal injections of the luetin reacted in a falsely positive manner. Following this, the extract fell into disuse and little more was heard of luetin until recent years when a new preparation with this name was investigated by a number of continental workers as well as by Hollander, 2 Kolmer and Taft, 3 and Gandy 4 of this country. This new luetin is known as organic luetin and is prepared by extracting a mature syphiloma of a rabbit's testicle, which is produced by the injection into the testicle of a strain of Spirochaeta pallida of known virulence. In order to obviate the possibility of the patient giving a falsely positive reaction because of a sensitization to |
