Acute Anatomic Breakdown of Motor End Plates in Hemorrhagic Shock

Autor:	Leo C. Massopust, Eugene Haushalter, Walter Zeit, John Schmitz, Eben J. Carey
Rok vydání:	1944
Předmět:	Chemistry Permeability (electromagnetism) Hemorrhagic shock Motor end plates Limited evidence Anatomy General Biochemistry Genetics and Molecular Biology
Zdroj:	Experimental Biology and Medicine. 56:115-118
ISSN:	1535-3699 1535-3702
DOI:	10.3181/00379727-56-14615
Popis:	SummaryThe limited evidence in this paper supports the claim that hemorrhagic shock profoundly alters the morphology of the motor end plates and finally produces loss of structural innervation of many muscle fibers in a single voluntary muscle. This histologic change is highly irregular in the different muscles of the rat, therefore large numbers of specimens from different muscles were teased. Gold staining masses of axonic materials drain out into and between the muscle fibers coincident in time with the loss of motor innervation due to the increased permeability of the end plates. The epilemmal axons, exhausted of their substances, are in many places likewise denuded of their hypolemmal end plates. There is therefore a real anatomic breakdown of many motor end plates and histologic alteration of certain skeletal muscles in hemorrhagic shock.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e66e7ea51e4c2f41a6dfc3a51cbf304a https://doi.org/10.3181/00379727-56-14615 Zobrazit plný text záznamu