Niedrig dosierte thrombolytische Therapie zur Wiederherstellung der Strombahn bei arteriellen Verschlüssen

Autor:	Ingrisch H, Mietaschk A, H. Hess
Rok vydání:	2008
Předmět:	Urokinase medicine.medical_specialty business.industry Streptokinase General Medicine medicine.disease Surgery Catheter Arterial occlusions Occlusion medicine Platelet aggregation inhibitor Thrombus business medicine.drug
Zdroj:	DMW - Deutsche Medizinische Wochenschrift. 105:787-791
ISSN:	1439-4413 0012-0472
Popis:	Acute and subacute arterial occlusions of between 4.5 and 29 cm long could be dissolved in 11 patients by infiltration of small amounts (4000 to 110 000 U) of streptokinase or urokinase directly into the thrombus using a catheter. Use of a Gruntzig catheter enabled dilatation of possible stenoses during the same session. In 3 femoro-popliteal obliterations where lysis and catheter dilatation did not lead to sufficiently patent lumina occlusion recurred. In 3 patients with wide-ranging obliteration of the femoral, popliteal and almost all the arteries of the calf almost complete revascularisation could be achieved. Only transient slight side effects of lysis and coagulation disturbances were observed systemically. For prophylaxis of reobliteration platelet aggregation inhibitors are given for pre- and long-term aftercare.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e646322b0dd34ec3f57c16304c57229e https://doi.org/10.1055/s-2008-1070752 Zobrazit plný text záznamu