| Autor: |
Galba Jean Beppe, Bertrand Poo Barga, Donatien Albert Atsamo, Christ-Roi Fedaski, Alice Irène Folefack, Nanou Gael Allah-Doum, Franklin Gamo Zemo, Alain Bertrand Dongmo |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
The Journal of Phytopharmacology. 12:1-10 |
| ISSN: |
2320-480X |
| DOI: |
10.31254/phyto.2023.12101 |
| Popis: |
Background: Piliostigma reticulatum (Fabaceae) is a plant used in Cameroon for the treatment of madness and migraine. Aims and Objectives: This study aims to evaluate the memory-enhancing and antioxidant activities of the hydroethanolic leaves extract of PR in the monosodium glutamate-induced Alzheimer's disease model. Materials and Methods: The Y-maze, Radial-arm maze and Novel object recognition tests were used to assess short, and long-term memory. At the end of the experiments, the brains of mice were scavenged for biochemical and histological analysis. Results: It was observed that the hydroalcoholic extract of PR leaf significantly reversed the percentage of spontaneous alternation compared to the negative control group at the different doses tested (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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