PLACEBO-DRIVEN CLINICAL TRIALS OF TRANSFER POINT GLUCAN #300 IN CHILDREN WITH CHRONIC RESPIRATORY PROBLEMS: ANTIBODY PRODUCTION

Autor: Král Vlastimil, Vetvicka Vaclav, Svozil Vladimir, Richter Josef, Rajnohova Dobiasova Lucie
Rok vydání: 2013
Předmět:
Zdroj: American Journal of Immunology. 9:43-47
ISSN: 1553-619X
DOI: 10.3844/ajisp.2013.43.47
Popis: The role of glucan in stimulation of immune reactio ns has been well-established. In this report, we fo cused on the antibody production in glucan-supplemented children with chronic respiratory problems. We measured the levels of salivary IgA, IgM and IgG in 40 children aged 8-12 years and evaluated the effe cts of 100 mg d -1 oral dose of glucan. We found a significant increa se in production of all tested antibodies in the glucan-stimulated group, but a decrease of anti body production in the control group. A thirty-day oral application of yeast-based natural immunomodulator β-glucan strongly stimulated the mucosal immunity of children with chronic respiratory problems.
Databáze: OpenAIRE