Spectral in vivo signature of carotenoids in visible light diffuse reflectance from skin in comparison to ex vivo absorption spectra
| Autor: | Jürgen Helfmann, Carina Reble, Stefan Andree |
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| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Photonics & Lasers in Medicine. 2 |
| ISSN: | 2193-0643 2193-0635 |
| DOI: | 10.1515/plm-2013-0032 |
| Popis: | To increase the carotenoid concentration in skin by drinking carrot juice to generate an optical response and to determine anThe first author of the presented study consumed carrot juice over a period of several weeks and during this time regularly performed optical reflection measurements on his palm. The spectroscopic measurements were carried out with a fiber-based sensor using a thermal light source. Absorption coefficients have been deduced from the diffuse reflectance data. Measurements were also performed on a β-carotene solution, on carrot juice and its extracted carotenoids. The correlation coefficient between carrot juice intake in liters and the optical skin signal was used to select an optimal wavelength for carotenoid detection (493 nm).AnDetection of carotenoids in skin is possible by diffuse reflectance measurements with a simple spectroscopic optical setup, as it is described in this article. As found by comparing different publications, several geometries for illumination and detection support carotenoid quantification. However, the fiber probe described here is not limited to carotenoid detection and it does not need arrangement of several optical elements such as lenses, mirrors or apertures and therefore requiring less effort for development. To eliminate the interference of hemoglobin, the authors suggest the combination of pressure and the described software method. Other publications have reported hemoglobin interference with respect to |
| Databáze: | OpenAIRE |
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