Reaction of swine to oil-adjuvanted inactivated foot-and-mouth disease virus vaccine inoculated by intramuscular and subcutaneous routes

Autor:	P. B. Capstick, R. Burrows, P. Gailiunas, P. D. McKercher
Rok vydání:	1971
Předmět:	Intramuscular route medicine.medical_specialty Inoculation General Medicine Biology biology.organism_classification Virology Serology Antibody response Medical microbiology Antigen medicine Foot-and-mouth disease virus Local Reaction
Zdroj:	Archiv f�r die gesamte Virusforschung. 35:364-377
ISSN:	1432-8798 0304-8608
DOI:	10.1007/bf01241917
Popis:	Local reactions at inoculation sites of swine vaccinated with foot-and-mouth disease antigens emulsified with oil adjuvant were examined at 7, 14, 32, 45, 62 and 90 days postinoculation. The serologic data indicate that either the subcutaneous or intramuscular route, as well as the different inoculation sites selected induce a similar antibody response. Lesions at all inoculation sites were characterized by subacute and chronic granulomatous tissue reaction and the continuous presence of oil vacuoles. There is little doubt that some degree of reaction at the site of inoculation is to be expected and thus the site and route are of utmost importance in reducing the possibility of a carcass blemish.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e5fda743ff63c9921da68ce31136372b https://doi.org/10.1007/bf01241917 Zobrazit plný text záznamu Full text from SpringerLink