| Popis: |
Plaque biolms is the primary etiology for periodontitis. Mechanical debridement procedures to treat periodontitis still remain the gold standard but adjunctive antimicrobial therapy is also required in certain cases. However the use of antibiotics has their own disadvantages of creating resistant bacterial forms as well as systemic side effects. Photodynamic therapy (PDT) is a novel non-invasive therapeutic approach which overcomes these problems. Photodynamic therapy (PDT) or photochemotherapy has increased pathogen specicity as well as site specicity and hence no systemic effects. PDTinvolves the use of a photosensitiser which on exposure to light of specic wavelength, gets activated, to form toxic oxygen species which further cause a localised photodamage and cell death. As PDT is with no localised as well as systemic adverse effects, its application in periodontal disease treatment continues to evolve into a mature clinical treatment modality. |
