Prevalence and phylogenic study of human T-lymphotropic virus 1 in patients with thalassemia in the northeast of Iran
| Autor: | Farshid Abedi, Hoda Gudarzi, Marzieh Rahimzadegan, Narges Valizadeh, Sayed-Hamidreza Mozhgani, Seyed Abdolrahim Rezaee |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
biology business.industry viruses Thalassemia 030106 microbiology biology.organism_classification HTLV antibodies medicine.disease Virology Phylogenetic distribution 03 medical and health sciences 0302 clinical medicine Blood transfusion history Virus type hemic and lymphatic diseases Human T-lymphotropic virus 1 Immunology Medicine Marital status In patient 030212 general & internal medicine business |
| Zdroj: | Future Virology. 12:253-258 |
| ISSN: | 1746-0808 1746-0794 |
| Popis: | Aim: This study aimed to investigate the frequency and phylogenetic distribution of human T-lymphotropic virus type 1 (HTLV-1) in thalassemia cases. Methods: Between 2006 and 2013, a total of 100 thalassemic individuals were investigated for HTLV-1 infections. Results: Four people (4%) were reactive for HTLV antibodies. No considerable correlation was seen between factors such as age, blood transfusion history, surgery, marital status, gender and blood types. All HTLV-1 sequences belonged to the transcontinental (A) subgroup in the cosmopolitan (a) subtype. Conclusion: In addition to phylogenetic distribution, our results demonstrate that the prevalence of HTLV-1 infection among thalassemia patients in Mashhad is higher than that of previous studies. |
| Databáze: | OpenAIRE |
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