Syntheses de sept pyrimidines deuteriees en position specifique
| Autor: | Jacqueline Hervieu, Marie-France Lautie-Mouneyrac, Pierre Dizabo, J. Dagaut, L. C. Leitch, Roger N-Renaud |
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| Rok vydání: | 1972 |
| Předmět: |
chemistry.chemical_classification
Base (chemistry) Stereochemistry Organic Chemistry Silver acetate General Medicine Biochemistry Medicinal chemistry Analytical Chemistry Catalysis chemistry.chemical_compound Deuterium chemistry Drug Discovery Reductive dechlorination Radiology Nuclear Medicine and imaging Spectroscopy |
| Zdroj: | Journal of Labelled Compounds. 8:365-378 |
| ISSN: | 1099-1344 0022-2135 |
| DOI: | 10.1002/jlcr.2590080303 |
| Popis: | The synthesis of seven deuteriopyrimidines of high isotopic purity was effected either by reductive dechlorination of chloropyrimidines with deuterium on a Pd/CaCO3 catalyst, deuterolysis of sulfonylhydrazinopyrimidines with mild base in D2 O or oxidation of hydrazinopyrimidines with silver acetate. |
| Databáze: | OpenAIRE |
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