Effect of FiO 2 in the measurement of VO 2 and VCO 2 using the E-COXV metabolic monitor

Autor: Juan Antonio Llompart-Pou, A. Colomar, I. Ayestarán, Joan Maria Raurich, M. Ferreruela
Rok vydání: 2017
Předmět:
Zdroj: Medicina Intensiva (English Edition). 41:461-467
ISSN: 2173-5727
DOI: 10.1016/j.medine.2017.08.007
Popis: Objective We evaluated the effect of changes in FiO2 on the bias and accuracy of the determination of oxygen consumption ( V ⋅ O 2 ) and carbon dioxide production ( V ⋅ CO 2 ) using the E-COVX monitor in patients with mechanical ventilation. Design Descriptive of concordance. Setting Intensive Care Unit. Patients or participants Patients with mechanical ventilation. Interventions We measured V ⋅ O 2 and V ⋅ CO 2 using the E-COVX monitor. Values recorded were the average in 5 min. Two groups of 30 patients. We analyzed: 1) the reproducibility in the measurement of V ⋅ O 2 and V ⋅ CO 2 at FiO2 0.4, and 2) the effect of the changes in FiO2 on the measurement of V ⋅ O 2 and V ⋅ CO 2 . Statistical analysis was performed using Bland and Altman test. Variables of main interest Bias and accuracy. Results 1) FiO2 0.4 reproducibility: The bias in the measurement of V ⋅ O 2 and V ⋅ CO 2 was 1.6 and 2.1 mL/min, respectively, and accuracy was 9.7 to −8.3% and 7.2 to −5.2%, respectively, and 2) effect of FiO2 on V ⋅ O 2 : The bias of V ⋅ O 2 measured at FiO2 0.4 and 0.6 was −4.0 mL/min and FiO2 0.4 and 0.8 was 5.2 mL/min. Accuracy between FiO2 0.4 and 0.6 was 11.9 to −14.1%, and between FiO2 0.4 and 0.8 was 43.9 to −39.7%. Conclusions The E-COVX monitor evaluates V ⋅ O 2 and V ⋅ CO 2 in critical patients with mechanical ventilation with a clinically acceptable accuracy until FiO2 0.6.
Databáze: OpenAIRE