Ion and Fluid Homeostasis in the Cochlea
| Autor: | Philine Wangemann, Daniel C. Marcus |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Cell type Endolymph Chemistry Cochlear duct Perilymph Cell biology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure otorhinolaryngologic diseases medicine Transduction (physiology) 030217 neurology & neurosurgery Ion transporter Cochlea Homeostasis |
| Zdroj: | Understanding the Cochlea ISBN: 9783319520711 |
| Popis: | The transduction of sound into nerve impulses requires an ionic environment that depends on a variety of ion transport processes in epithelial and endothelial cells of the cochlea. Specific ion transport functions occur in specific cell types that coordinate the production and maintenance of endolymph, which is the fluid in the lumen of the cochlear duct that supports the sensory transduction process. The critical nature of these ion transport processes is underscored by observations of hearing loss when ion transport mechanisms malfunction as a result of mutations, drug exposure, or hormonal imbalance. This chapter describes our basic understanding of salient ion transport processes and their regulation by hormones and other regulatory pathways. |
| Databáze: | OpenAIRE |
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