Steroid Borates II. Process Applications

Autor:	Muller Siegfried A, Lewis J. Leeson, George M. Sieger, James A. Lowery
Rok vydání:	1961
Předmět:	Chemistry Scientific method medicine.medical_treatment Aqueous solubility medicine Pharmaceutical Science chemistry.chemical_element Moiety Organic chemistry Boron Steroid
Zdroj:	Journal of Pharmaceutical Sciences. 50:606-608
ISSN:	0022-3549
DOI:	10.1002/jps.2600500717
Popis:	Alkaline steroid borates, in addition to exhibiting high aqueous solubility, have been found useful in certain chemical processes. These include separation of 16α, 17α-hydroxylated steroids from steroids lacking the cis glycol moiety at C16 and C17, and the preparation of 21-monoesters of 16α-hydroxylated adrenocorticoids. Both of these techniques are based upon the complexing of 16α, 17α-dihydroxy steroids with alkaline borates.
Databáze:	OpenAIRE
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