Cytotoxic activity of neo-clerodane diterpenoids
| Autor: | Maria Dolores Garcia‐Gravalos, Arturo San Feliciano, Marina Gordaliza, Maria L. De la Puente, JoséM. Miguel del Corral |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Traditional medicine
biology Chemistry Scrophulariaceae Stereochemistry fungi Organic Chemistry Clinical Biochemistry Pharmaceutical Science Linaria saxatilis Pharmacognosy biology.organism_classification Biochemistry In vitro Terpene chemistry.chemical_compound Drug Discovery Molecular Medicine Cytotoxic T cell Neoplastic cell Diterpene Molecular Biology |
| Zdroj: | Bioorganic & Medicinal Chemistry Letters. 7:1649-1654 |
| ISSN: | 0960-894X |
| DOI: | 10.1016/s0960-894x(97)00277-1 |
| Popis: | Several neo-clerodane diterpenoids isolated from extracts of roots and aerial parts of Linaria saxatilis var. glutinosa, as well as some semisynthetic derivatives, exhibited in vitro growth inhibition against different neoplastic cell cultures. A number of substances showed IC50 values under 1μM. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect