Capsules Dosage Form
| Autor: | S.W. Hoag |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Computer science
business.industry Context (language use) 02 engineering and technology Capsule Dosage Form 021001 nanoscience & nanotechnology Dosage form Manufacturing engineering 020401 chemical engineering Drug development Pill Drug product 0204 chemical engineering 0210 nano-technology business Pharmaceutical industry |
| Popis: | The use of capsules goes back to the early days of pharmacy, and since these early days capsules have evolved significantly to meet the current needs of the patient and pharmaceutical industry. Some of the early developments in capsule technology occurred as pharmacy evolved from dispensing compounded medication to the dispensing of manufactured products; during this change there were numerous advances in gelatin, capsule shell design and high speed manufacturing equipment. Currently the pharmaceutical industry is undergoing a sea change as the blockbuster drugs become harder and harder to find, more of the value of a drug product comes from a dosage form with advanced delivery capabilities that can improve therapeutic outcomes. For example, capsule filling technologies have been developed for the manufacture of multiparticulate delivery systems, multiple dosage form systems such as a tablet in a capsule, combination products and delivery systems with multiphasic release rates. In addition, capsules have always played an important role in the drug development process because hand filling or semiautomatic filling capsule formulations have minimal requirements and can be quickly developed. Given this context, the chapter will discuss the capsule dosage form in the drug development process starting with a discussion of gelatin, the different types of capsules shells, formulation and manufacturing. Also, we will discuss specialty capsules and capsule fills. |
| Databáze: | OpenAIRE |
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