| Autor: |
Saoussen Cheikh Mhammed, Naceur Rouatbi, Asma Migaou, Sameh Jobeur, Ahmed Ben Saad, Nesrine Fahem |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Journal of Lung, Pulmonary & Respiratory Research. 6:81-85 |
| ISSN: |
2376-0060 |
| DOI: |
10.15406/jlprr.2019.06.00213 |
| Popis: |
Introduction The superior vena cava syndrome SVCS is a set of signs related to the obstruction of the upper cava current caused by a compression an invasion or a thrombosis of the superior vena cava Its etiologies are numerous but dominated by neoplastic causes mainly of bronchopulmonary origin Aim of the work The aim of this study is to evaluate survival and to identify the prognostic factors of superior vena cava syndrome in patients with lung cancer We also propose to draw up the clinical profile as well as the therapeutic management in SVCS of malignant origin Materials and methods A total of patients with SVCS complicating primary bronchial cancer were hospitalized in the Pneumology Department at Fattouma Bourguiba University Hospital during a period of years Results The results showed the existence of a clear male predominance and an average age of years Smoking was found in of cases The superior vena cava syndrome revealed a neoplasm in of cases and it was metachronous in of cases Median survival was months In univariate study survival was reduced in patients having general health impairment with Performans Status PS score ge signs of severity of SVCS altered respiratory function chronic respiratory failure histological type of non small cell lung carcinoma and exclusive symptomatic treatment for bronchopulmonary cancer Multivariate analysis revealed that gender smoking PS score and signs of severity were independent prognostic factors Conclusion The management of the SVCS is multidisciplinary It requires medical treatment whose effectiveness is still uncertain and radiotherapy which is considered the gold standard of treatment fIntroduction The superior vena cava syndrome SVCS is a set of signs related to the obstruction of the upper cava current caused by a compression an invasion or a thrombosis of the superior vena cava Its etiologies are numerous but dominated by neoplastic causes mainly of bronchopulmonary origin Aim of the work The aim of this study is to evaluate survival and to identify the prognostic factors of superior vena cava syndrome in patients with lung cancer We also propose to draw up the clinical profile as well as the therapeutic management in SVCS of malignant origin Materials and methods A total of patients with SVCS complicating primary bronchial cancer were hospitalized in the Pneumology Department at Fattouma Bourguiba University Hospital during a period of years Results The results showed the existence of a clear male predominance and an average age of years Smoking was found in of cases The superior vena cava syndrome revealed a neoplasm in of cases and it was metachronous in of cases Median survival was months In univariate study survival was reduced in patients having general health impairment with Performans Status PS score ge signs of severity of SVCS altered respiratory function chronic respiratory failure histological type of non small cell lung carcinoma and exclusive symptomatic treatment for bronchopulmonary cancer Multivariate analysis revealed that gender smoking PS score and signs of severity were independent prognostic factors Conclusion The management of the SVCS is multidisciplinary It requires medical treatment whose effectiveness is still uncertain and radiotherapy which is considered the gold standard of treatment for SVCS nbsp Introduction The superior vena cava syndrome SVCS is a set of signs related to the obstruction of the upper cava current caused by a compression an invasion or a thrombosis of the superior vena cava Its etiologies are numerous but dominated by neoplastic causes mainly of bronchopulmonary origin Aim of the work The aim of this study is to evaluate survival and to identify the prognostic factors of superior vena cava syndrome in patients with lung cancer We also propose to draw up the clinical profile as well as the therapeutic management in SVCS of malignant origin Materials and methods A total of patients with SVCS complicating primary bronchial cancer were hospitalized in the Pneumology Department at Fattouma Bourguiba University Hospital during a period of years Results The results showed the existence of a clear male predominance and an average age of years Smoking was found in of cases The superior vena cava syndrome revealed a neoplasm in of cases and it was metachronous in of cases Median survival was months In univariate study survival was reduced in patients having general health impairment with Performans Status PS score ge signs of severity of SVCS altered respiratory function chronic respiratory failure histological type of non small cell lung carcinoma and exclusive symptomatic treatment for bronchopulmonary cancer Multivariate analysis revealed that gender smoking PS score and signs of severity were independent prognostic factors Conclusion The management of the SVCS is multidisciplinary It requires medical treatment whose effectiveness is still uncertain and radiotherapy which is considered the gold standard of treatment for SVCS yndrome SVCS is a set of signs related to the obstruction of the upper cava current caused by a compression an invasion or a thrombosis of the superior vena cava Its etiologies are numerous but dominated by neoplastic causes mainly of bronchopulmonary origin Aim of the work The aim of this study is to evaluate survival and to identify the prognostic factors of superior vena cava syndrome in patients with lung cancer We also propose to draw up the clinical profile as well as the therapeutic management in SVCS of malignant origin Materials and methods A total of patients with SVCS complicating primary bronchial cancer were hospitalized in the Pneumology Department at Fattouma Bourguiba University Hospital during a period of years Results The results showed the existence of a clear male predominance and an average age of years Smoking was found in of cases The superior vena cava syndrome revealed a neoplasm in of cases and it was metachronous in of cases Median survival was months In univariate study survival was reduced in patients having general health impairment with Performans Status PS score ge signs of severity of SVCS altered respiratory function chronic respiratory failure histological type of non small cell lung carcinoma and exclusive symptomatic treatment for bronchopulmonary cancer Multivariate analysis revealed that gender smoking PS score and signs of severity were independent prognostic factors Conclusion The management of the SVCS is multidisciplinary It requires medical treatment whose effectiveness is still uncertain and radiotherapy which is considered the gold standard of treatment nbsp |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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