Comparative Account of the Genotoxic and Antimicrobial Effects of Silver Nanoparticles Synthesized from Extract of Pleurotus Ostreatus and Chemically Synthesized Nanoparticles
| Autor: | Bikram Dhara, Ishita Roy, Amrita Maity |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
030102 biochemistry & molecular biology Nanoparticle Cell Biology Biology medicine.disease_cause biology.organism_classification Antimicrobial Silver nanoparticle 03 medical and health sciences 030104 developmental biology medicine Allium Pleurotus ostreatus Escherichia coli Bacteria Nuclear chemistry Antibacterial agent |
| Zdroj: | Cell and Tissue Biology. 15:77-89 |
| ISSN: | 1990-5203 1990-519X |
| Popis: | Recently, metallic nanoparticles have gained attention for its potential as antibacterial agent. However, because of the risk it poses towards environment, biologically synthesised nanoparticles have got the preference. Green synthesis of silver nanoparticles (AgNPs) from edible mushrooms are considered to be cost effective and eco-friendly. In this study, we found that biologically synthesised AgNPs from the water extracts of Pleurotus ostreatus exhibited less cytotoxic effect on mitotic chromosomes of Allium cepa root meristem, when compared to chemically synthesised AgNPs. The synthetic AgNPs possesses high genotoxic effect including spindle disruption, sticky metaphase chromosomes, multipolarity, early and late anaphase etc. Results also prove that these biologically synthesised AgNPs possess better antimicrobial properties than the chemically synthesized one against both the gram-positive (Bacillus, Staphylococcus) and the gram-negative bacteria (Escherichia coli, Klebsiella). |
| Databáze: | OpenAIRE |
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