Multi-purpose functionality for the structural elaboration of the piperazine-2,5-dione motif

Autor:	John A. Elix, Paul B. Huleatt, Christina L. L. Chai
Rok vydání:	2003
Předmět:	Stereochemistry Organic Chemistry Heteroatom Substituent chemistry.chemical_element Alkylation Biochemistry Ion formation Piperazine chemistry.chemical_compound Motif (narrative) chemistry Drug Discovery Carbon Elaboration
Zdroj:	Tetrahedron Letters. 44:263-265
ISSN:	0040-4039
Popis:	Mild methods for controlled C- and N-alkylation of 3-benzyloxycarbonylpiperazine-2,5-diones are reported. The benzyloxylcarbonyl substituent can also serve as latent functionality for N-acyliminium ion formation and subsequent trapping enables installation of new carbon and/or heteroatom substituents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e58e168c4c26b7986678f3ccf171a372 https://doi.org/10.1016/s0040-4039(02)02571-6 Zobrazit plný text záznamu Full Text from ScienceDirect