High impact and effectiveness of Gavac™ vaccine in the national program for control of bovine ticks Rhipicephalus microplus in Venezuela
| Autor: | Yusmel Sordo, Marisela Suárez, Ruben Cartaya, Eli Rubio, Carlos Montero, Eulogio Pimentel, Ricardo Ramírez, Danny Pérez, Madaisy Cueto, Yamila Carpio, Vladimir Cordova, Fabio Barrios, Ernesto Mantilla, Adelquis Vielma, Jorge Luis Gonzalez, Héctor Machado, Ariel Cruz, Danay Callard, Pedro Puente, Julio Rubi, Claudibeth Escalona, Zoila Abad, Carlos Antonio Gil, Jonathan Bermudes, Mario Pablo Estrada, Mariela Palacios, Yader Salazar, Carlos Borroto, Yanaysi Ceballo, Boris Ramos, José de la Torre Rodríguez, Yermina Carrillo, A. Hernandez, Ernesto González, Ricardo Pina, Nerio Segura, Yamilka Ramirez, Antonio Morales, Mónica Navarro, Milagros Vargas, Roberto Basulto Baker, Andrés Castillo, Eduardo Smith, Osvaldo Oliva, Amaurys Cardoso |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Integrated pest management Gavac vaccine Veterinary medicine education.field_of_study General Veterinary biology business.industry Acaricide 030231 tropical medicine Population Tick biology.organism_classification 03 medical and health sciences 030104 developmental biology 0302 clinical medicine parasitic diseases Rhipicephalus microplus Animal Science and Zoology Tick Control Livestock education business |
| Zdroj: | Livestock Science. 187:48-52 |
| ISSN: | 1871-1413 |
| DOI: | 10.1016/j.livsci.2016.02.005 |
| Popis: | The 80% of the world's cattle population (approximately 1281 million), 80% are at risk for ticks and tick-borne diseases. Over a decade ago, the estimated global costs of control measures and productivity losses amounted to $7.0 billion USD annually (7 USD/head/years). Tick control in livestock remains, to a large extent, based on chemical acaricides, but their use in combination with anti-tick vaccines and utilization of host resistance to ticks should reduce dependency on chemical tick control. Currently the only effective vaccine in the market to control tick populations is Gavac™. The immunogen Bm86 used to produce Gavac™ had already been tested in controlled experiments and field trials demonstrating its effectiveness. In this study Gavac™ vaccine was used for the first time in a national program, namely the integrated program for bovine tick control, which included more than 1.9 million bovines, spread over 18 states of the Republic of Venezuela. After two years of implementation of the program, 38835 cattle farms were included, and 83.7% of chemical acaricide were reduced. The program had a major impact, saving 81.5% of the estimated cost of the traditional chemical tick control treatments. A reduction of more than 260 t of chemical acaricides was attained. These results strongly support the use of vaccine for tick control in integrated control programs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect