Antioxidative activity of flavones and flavonolsin vitro

Autor:	Takako Yokozawa, Mineo Shimizu, Zhong Wu Liu, Erbo Dong
Rok vydání:	1997
Předmět:	inorganic chemicals Pharmacology chemistry.chemical_classification Antioxidant Chemistry Stereochemistry Chemical structure medicine.medical_treatment fungi Flavonoid Pharmacognosy Flavones In vitro Lipid peroxidation chemistry.chemical_compound Flavonols Biochemistry medicine
Zdroj:	Phytotherapy Research. 11:446-449
ISSN:	1099-1573 0951-418X
Popis:	Forty-one flavonoids of the flavone and flavonol types were investigated for their antioxidative activity using a lipid peroxidation generation system mediated by the addition of H2O2/Fe2+ to rat liver homogenate. The results showed that both types specifically and markedly reduced the production of peroxidants induced by H2O2, Fe2+ or a Fenton-type reaction. The scavenging ability of these compounds was found to be associated closely with their chemical structure, especially the number of hydroxyl groups linked to the basic skeleton. However, there were some exceptions, implying that not only hydroxyl groups but also their configuration determines the activity. © 1997 John Wiley & Sons, Ltd.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e5822f91da4329c83d0703a2608c5a4d https://doi.org/10.1002/(sici)1099-1573(199709)11:6<446::aid-ptr128>3.0.co Zobrazit plný text záznamu Plný text