Preparation and characterization of biodegradable scaffolds of poly(lactide-co-glycolide) 50:50 and hydroxyapatite for dental applications
| Autor: | Nayanabhirama Udupa, Kishore Ginjupalli, Ranjith Kumar Averineni, K. Mahalinga Bhat |
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| Rok vydání: | 2013 |
| Předmět: |
Poly lactide co glycolide
Materials science Extraction (chemistry) General Physics and Astronomy Biodegradable composites Surfaces Coatings and Films PLGA chemistry.chemical_compound Chemical engineering chemistry Biodegradable scaffold Ceramics and Composites Degradation (geology) Biomedical engineering |
| Zdroj: | Composite Interfaces. 21:31-44 |
| ISSN: | 1568-5543 0927-6440 |
| Popis: | In the present study, biodegradable scaffolds of poly(lactide-co-glycolide) PLGA 50:50 with acidic microclimate controlling additives were prepared and characterized for their degradation behavior, physical, and mechanical properties. Results indicate that scaffolds with acidic microclimate controlling additives undergo degradation without large variation in pH of the surrounding medium. Results also indicated that microclimate controlling additives did not significantly alter the physical and mechanical properties of the scaffolds. From the results, it can be concluded that PLGA 50:50 scaffolds with acidic microclimate controlling additives can be used as root replicas after the tooth extraction. |
| Databáze: | OpenAIRE |
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