| Autor: |
M. Porres Aguilar, David Jiménez, Lisa K. Moores, Roger D. Yusen, Jorge Lima, Behnood Bikdeli, M. Aramberri, Manuel Monreal, Aitor Ballaz, Andrés Quezada |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Thrombosis Research. 182:7 |
| ISSN: |
0049-3848 |
| DOI: |
10.1016/j.thromres.2019.09.020 |
| Popis: |
Importance The optimal cut-off for systolic blood pressure (SBP) to define high-risk pulmonary embolism (PE) remains to be defined. Objectives To evaluate the relationship between SBP on admission and short-term mortality and other cardiovascular events in patients with acute symptomatic PE. Design, Setting and Participants The Registro Informatizado de la Enfermedad TromboEmbolica (RIETE) Registry is an ongoing, multi-center, international, prospective registry of consecutive patients with symptomatic, objectively confirmed, acute venous thromboembolism (VTE). The current study included 39,257 patients from RIETE with acute symptomatic PE between 2001 and 2018. Main Outcomes and Measures Primary outcomes included all-cause and PE-specific 30-day mortality. Secondary outcomes included major bleeding and recurrent venous thromboembolism (VTE). Results There was a linear inverse relationship between admission SBP and 30-day all-cause and PE-related mortality that persisted after multivariable adjustment. Patients in the lower SBP strata had higher rates of all-cause death (reference: SBP 120-129 mmHg) (adjusted odds ratio [OR] 2.9, 95% confidence interval [CI] 2.0-4.2 for SBP Conclusions In patients with acute symptomatic PE, a low SBP portends an increased risk of all-cause and PE-related mortality. The highest mortality was observed in patients with SBP |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full Text from ScienceDirect