Gallium-67 Uptake in Histological Variants of Non-Hodgkin’s Lymphoma – A Correlative Study
| Autor: | Geoffrey M. Currie, Uzma Afzal, Humayun Bashir, Basit Iqbal, M. Khalid Nawaz, Muhammad Numair Younis, Samina Mansoor, Janelle Wheat |
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| Rok vydání: | 2012 |
| Předmět: |
Pathology
medicine.medical_specialty Chemotherapy medicine.diagnostic_test business.industry medicine.medical_treatment medicine.disease Scintigraphy Lymphoma Non-Hodgkin's lymphoma medicine.anatomical_structure hemic and lymphatic diseases Biopsy medicine Neoplasm Histopathology Bone marrow business |
| Zdroj: | The Open Nuclear Medicine Journal. 4:1-4 |
| ISSN: | 1876-388X |
| DOI: | 10.2174/1876388x01204010001 |
| Popis: | Introduction: The malignant lymphomas are the fifth most common neoplasm in both men and women. Staging, re-staging and treatment response evaluation pose a difficult task in many patients of lymphomas. Histological variants in both Hodgkin's and Non-Hodgkin's types of lymphoma greatly affect the response to treatment and overall prognosis. Objective: This study was conducted to correlate the degree of abnormal Gallium-67 uptake with the histological variants of non-Hodgkin's lymphoma. This project was a part of the study to see the ability of Gallium-67 scintigraphy to predict the response to chemotherapy early in the course of therapy. Material & Methods: 65 patients were included in the study with a mean age of 25 years. All patients had undergone medical imaging, bone marrow biopsy and histopathology. Results: Sixty-five patients were classified according to the REAL classification. 11 patients were of T-cell type, 50 were of B-cell type and 4 were anaplastic. 46 showed gallium-67 uptake in the lesions, whereas 19 (29.2%) had no discernable Gallium-67 uptake. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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