FAILURE OF FOLIC ACID ANTAGONIST TO INTERFERE WITH THE ACTION OF TESTOSTERONE PROPIONATE ON THE COMBS AND TESTES OF YOUNG COCKERELS1

Autor:	M. X. Zarrow, I. B. Koretsky, I. G. Zarrow
Rok vydání:	1951
Předmět:	Testosterone propionate medicine.medical_specialty medicine.drug_class media_common.quotation_subject Appetite Biology Androgen chemistry.chemical_compound Endocrinology medicine.anatomical_structure chemistry Biotin Prostate Estrogen Internal medicine medicine Oviduct Testosterone media_common
Zdroj:	Endocrinology. 48:125-132
ISSN:	1945-7170 0013-7227
DOI:	10.1210/endo-48-2-125
Popis:	THE failure to obtain growth of the female reproductive tract after treatment with estrogen in the absence of folic acid has been well established. Since the initial report of Hertz and Sebrell (1944) on the inability of estrogen to stimulate growth of the oviduct of folic acid deficient chicks, confirmation has been obtained with the use of both synthetic diets and folic acid analogues. This inhibition of the growth promoting action of estrogen on the female reproductive tract has been observed in the frog (Goldsmith, Schreiber and Nigrelli, 1948), the chick (Hertz and Sebrell, 1944; Hertz, 1945, 1948; Andrus and Zarrow, 1949), the rat (Hertz and Tullner, 1949) and the monkey (Hertz, 1948; Zarrow, Hisaw and Salhanick, 1949). The role of folic acid in androgen induced growth of the male accessories has not been so clearly defined. Goldsmith, Black and Nigrelli (1949) have reported a failure to obtain androgen stimulated growth of the prostate in folic acid deficient mice
Databáze:	OpenAIRE
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