Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria
| Autor: | Nira R. Pollock, Rose A. Lee, Nicolaas M. Angenent-Mari, Peter Q. Nguyen, Nina M. Donghia, Jeffrey D. Dvorin, Helena de Puig, James J. Collins, Catherine M. Klapperich, James P. McGee |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Multidisciplinary biology business.industry 030231 tropical medicine Plasmodium vivax Plasmodium falciparum Plasmodium malariae biology.organism_classification medicine.disease Plasmodium ovale Plasmodium Virology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine parasitic diseases medicine Parasite hosting business Asymptomatic carrier Malaria |
| Zdroj: | Proceedings of the National Academy of Sciences. 117:25722-25731 |
| ISSN: | 1091-6490 0027-8424 |
| DOI: | 10.1073/pnas.2010196117 |
| Popis: | Asymptomatic carriers of Plasmodium parasites hamper malaria control and eradication. Achieving malaria eradication requires ultrasensitive diagnostics for low parasite density infections ( |
| Databáze: | OpenAIRE |
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