In Vitro and in Vivo Sensitivity of the Fowl Typhoid Organism, S. Gallinarum, to Antibiotics

Autor: Paul J. Glantz, Stephen Gordeuk
Rok vydání: 1955
Předmět:
Zdroj: Poultry Science. 34:880-890
ISSN: 0032-5791
DOI: 10.3382/ps.0340880
Popis: IN A study on the effect of antibiotics against the causative agent of fowl typhoid, S. gallinarum, Prier and Alberts (1951) found that aureomycin was more effective in vitro than streptomycin and penicillin. As a prophylactic treatment with chicks, aureomycin reduced losses approximately 50 percent. Jones et al. (1944) reported that streptomycin in sufficient concentration protected 11-day-old chick embryos against fowl typhoid. Milner and Shaffer (1953) in a study with S. typhimurium report that Chloromycetin is readily absorbed from the alimentary tract, establishing bacteriostatic blood levels, but only slightly affecting the viable (S. typhimurium) bacteria being excreted in feces of chicks. Chloromycetin did exert a definite effect against fatal outcome of the disease. Polymyxin B acted in the opposite manner, being poorly absorbed, decreasing drastically the bacteria excreted and having little effect on fatalities. In combination, these two antibiotics apparently suppressed the infection completely for several days, but mortality always …
Databáze: OpenAIRE