| Popis: |
Stereotactic radiosurgery has a well-defined and growing role in the treatment of intracranial meningiomas, being used as both a first-line option and a second-line treatment for surgical residue and relapsed tumours. However, stereotactic radiosurgery for meningioma may be burdened by toxicity-related side effects, which are analysed in this chapter, following a review of the relevant PubMed articles published from 1998 to 2020. The most significant documented side effects are cerebral oedema, radionecrosis, vascular lesions, cranial nerve damage and malignant transformation. These are analysed in terms of type, incidence, aetiology, mode of onset and predictability features, with a view to providing information for proper pretreatment selection of patients and putting in place the appropriate treatment measures at the time of their appearance. |
