Fabrication and in vivo demonstration of microchip-embedded smart electrode device for neural stimulation in retinal prosthesis
| Autor: | Jun Ohta, Toshihiko Noda, Shinya Nishimura, Yasuo Terasawa, Yukari Nakano, Takashi Tokuda, Kiyotaka Sasagawa, Makito Haruta |
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| Rok vydání: | 2017 |
| Předmět: |
010302 applied physics
Brain activation Fabrication Materials science ComputerSystemsOrganization_COMPUTERSYSTEMIMPLEMENTATION business.industry 010401 analytical chemistry technology industry and agriculture Integrated circuit 01 natural sciences humanities 0104 chemical sciences law.invention CMOS Hardware_GENERAL law Retinal Prosthesis 0103 physical sciences Neural stimulation Electrode Hardware_INTEGRATEDCIRCUITS Electrode array Optoelectronics business |
| Zdroj: | BioCAS |
| Popis: | A smart electrode device for use as a retinal prosthesis was fabricated and demonstrated. As a dedicated CMOS microchip is embedded in the smart electrode, each electrode on the electrode array works as an active component individually. Operation of the smart electrode, such as selecting target electrodes and adjusting the stimulus intensity, can be controlled by external control signals from bus wirings. A smart electrode array for an animal experiment was specially designed to proof the stimulus function of the smart electrode. An in vivo demonstration using the fabricated electrode was successfully performed. Brain activation was observed as a response to retinal stimulation. |
| Databáze: | OpenAIRE |
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