Association of Serum Albumin with Short-Term Outcome of Ischemic Stroke

Autor: Mohammad Ahtashamul Haque, Amir Hossain, Muhammad Enayet Hussain, Riaz Ferdaus, Quazi Deen Mohammad, Muhammad Abdul Momen Khan, Afm Al Masum Khan, Khairul Kabir Patwari, Dewan Md Elyas, Atm Hasibul Hasan, Bakhtiar Azam, Sirajee Shafiqul Islam
Rok vydání: 2019
Předmět:
Zdroj: Journal of National Institute of Neurosciences Bangladesh. 5:101-105
ISSN: 2410-8030
Popis: Background: Serum albumin is proved to be a neuroprotective substance in experimental studies in focal cerebral ischemia. Objective: The aim of this study was to find out any association of serum albumin with the short term outcome of ischemic stroke. Methodology: This observational study was conducted in the Department of Neurology and Department of Internal Medicine at Dhaka Medical College Hospital, Dhaka from January 2011 to December 2011. A total of fifty consecutive patient with first ever ischemic stroke were included. Short term outcome was measured on day 7 using the modified Rankin Scale (mRS) and poor outcome was defined as mRS score 4 to 6 or death. Serum albumin was measured within 24 hours of onset of stroke. Result: Serum albumin was found to be significantly associated with the short-term outcome of ischemic stroke [P-value of Chi square (df = 1) was 0.010]. On logistic regression analysis, SA level [p = 0.018, Odds Ratio (OR) =5.817; 95% confidence interval: 1.348 to 25.106] remained significantly and positively associated with the short-term outcome of ischemic stroke. Conclusion: Serum albumin is significantly associated with the short-term outcome of ischemic stroke and lower level predicts poor outcome and higher level predicts good outcome. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 101-105
Databáze: OpenAIRE