Effects of active substances fromStaphylococcus aureus (protein a and peptidoglycan) on neurotransmitter-induced contractions of smooth muscles
| Autor: | M. F. Shuba, I. B. Filippov, T. L. Davydovskaya, T. A. Lyubchenko, L. S. Kholodnaya, V. K. Pozur |
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| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
biology Physiology Chemistry General Neuroscience Myometrium Cell membrane chemistry.chemical_compound Endocrinology medicine.anatomical_structure Oxytocin Internal medicine medicine biology.protein Myocyte Peptidoglycan Protein A Neurotransmitter Acetylcholine medicine.drug |
| Zdroj: | Neurophysiology. 28:22-26 |
| ISSN: | 1573-9007 0090-2977 |
| Popis: | Modulatory effects of protein A (PA) and peptidoglycan (PG) fromStaphylococcus aureus on the smooth muscle contractions elicited by neurotransmitters were studied. PA and PG were found to suppress the myometrium smooth muscle contractions elicited by acetylcholine applications. The effects of the substances on the contractions were due to non-competitive inhibition through an enhancement of the potassium-dependent conductance of the smooth muscle cell membrane. PA and PG did not affect the myometrium contractions elicited by oxytocin, or the contractions of the coronary arteries elicited by acetylcholine or noradrenaline. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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