Covalently Bonded Platinum(II) Complexes of -Amino Acids and Peptides as a Potential Tool for Protein Labeling

Autor:	Martin Albrecht, Gabriela Guillena, Gema Rodríguez, Gerard van Koten
Rok vydání:	2002
Předmět:	chemistry.chemical_classification Stereochemistry Biomolecule Organic Chemistry chemistry.chemical_element General Chemistry Nuclear magnetic resonance spectroscopy Protein labeling Catalysis Amino acid chemistry Covalent bond Platinum Carbon Biosensor
Zdroj:	Chemistry - A European Journal. 8:5368-5376
ISSN:	1521-3765 0947-6539
Popis:	Arylplatinum complexes have been covalently bonded to the N and C termini and to the -carbon of various amino acid derivatives. These organometallic-functionalized amino acid compounds can be converted into the corresponding free amino acids under both basic and acidic conditions; this demonstrates the excellent stability properties of these biomolecules. Due to the NMRactivity displayed by the 195 Pt
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e4dcf6ee07f47e33c2d6c41d22d34ad9 https://doi.org/10.1002/1521-3765(20021202)8:23<5368::aid-chem5368>3.0.co Zobrazit plný text záznamu Plný text