Covalently Bonded Platinum(II) Complexes of -Amino Acids and Peptides as a Potential Tool for Protein Labeling
Autor: | Martin Albrecht, Gabriela Guillena, Gema Rodríguez, Gerard van Koten |
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Rok vydání: | 2002 |
Předmět: | |
Zdroj: | Chemistry - A European Journal. 8:5368-5376 |
ISSN: | 1521-3765 0947-6539 |
Popis: | Arylplatinum complexes have been covalently bonded to the N and C termini and to the -carbon of various amino acid derivatives. These organometallic-functionalized amino acid compounds can be converted into the corresponding free amino acids under both basic and acidic conditions; this demonstrates the excellent stability properties of these biomolecules. Due to the NMRactivity displayed by the 195 Pt |
Databáze: | OpenAIRE |
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