669Rheumatic Heart Disease outcomes in Australia: a linked data analysis
| Autor: | Jonathan R. Carapetis, Rebecca Seth, Joseph Hung, Jeffrey Cannon, Anna P. Ralph, Daniela Bond-Smith, Ingrid Stacey, Kevin Murray, Judith M. Katzenellenbogen |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | International Journal of Epidemiology. 50 |
| ISSN: | 1464-3685 0300-5771 |
| Popis: | Background Rheumatic Heart Disease (RHD), a chronic acquired heart-valve disease, is a major contributor to morbidity and mortality among Indigenous Australians. We estimate the probability and determinants of progressing from RHD diagnosis to cardiovascular complications/death in the Australian population, addressing methodological shortcomings in existing evidence. Methods This retrospective cohort study used linked RHD register, hospital and death data from five Australian jurisdictions. Cardiovascular complications (heart failure, stroke, endocarditis, atrial fibrillation) and all-cause mortality were measured for people aged Results 1718 RHD cases aged Conclusions Competing risks methods applied to linked data have provided the most comprehensive multi-jurisdictional estimates of RHD progression to cardiovascular complications/death in Australia. Risk of cardiovascular events was highest in metropolitan areas but clinical history of ARF was associated with reduced risk of progression. Key messages Despite access to the world-class Australian healthcare system, one-fifth of initially uncomplicated RHD diagnoses will progress to one of the complications examined within 8years |
| Databáze: | OpenAIRE |
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