Synthesis and biological activity of N-(2-acyloxycyclohexyl)-N-(2-aminoethyl)carboxamides
Autor: | E. Yu. Afanas’eva, O. S. Samarova, N. Yu. Borisova, E. Ya. Borisova, G. A. Fedorova, G. A. Vasil’eva, A. I. Ivanova, E. V. Arzamastsev |
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Rok vydání: | 2015 |
Předmět: | |
Zdroj: | Russian Chemical Bulletin. 64:92-98 |
ISSN: | 1573-9171 1066-5285 |
Popis: | Cyclohexene oxide ring opening with N,N-dialkylethane-1,2-diamines and subsequent N,O-acylation give rise to N-(2-acyloxycyclohexyl)-N-(2-aminoethyl)carboxamides. These compounds possess pronounced antiarrhythmic activity and low toxicity. |
Databáze: | OpenAIRE |
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