Synthesis and biological activity of N-(2-acyloxycyclohexyl)-N-(2-aminoethyl)carboxamides

Autor: E. Yu. Afanas’eva, O. S. Samarova, N. Yu. Borisova, E. Ya. Borisova, G. A. Fedorova, G. A. Vasil’eva, A. I. Ivanova, E. V. Arzamastsev
Rok vydání: 2015
Předmět:
Zdroj: Russian Chemical Bulletin. 64:92-98
ISSN: 1573-9171
1066-5285
Popis: Cyclohexene oxide ring opening with N,N-dialkylethane-1,2-diamines and subsequent N,O-acylation give rise to N-(2-acyloxycyclohexyl)-N-(2-aminoethyl)carboxamides. These compounds possess pronounced antiarrhythmic activity and low toxicity.
Databáze: OpenAIRE