Isometric skeletal muscle force measurement in primary myopathies
| Autor: | Paul A. Iaizzo, Hans F. Ginz, William K. Durfee, Kathi Schweikert |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
030506 rehabilitation
medicine.medical_specialty Dysferlinopathy Physiology Isometric exercise Inflammatory myopathy 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Physical medicine and rehabilitation Mitochondrial myopathy Physiology (medical) Internal medicine Medicine Facioscapulohumeral muscular dystrophy Muscular dystrophy Myopathy business.industry Skeletal muscle medicine.disease medicine.anatomical_structure Cardiology Neurology (clinical) medicine.symptom 0305 other medical science business 030217 neurology & neurosurgery |
| Zdroj: | Muscle & Nerve. 53:913-917 |
| ISSN: | 0148-639X |
| DOI: | 10.1002/mus.24954 |
| Popis: | INTRODUCTION In myopathy patients, it is useful to measure skeletal muscle forces. Conventional methods require voluntary muscle activation, which can be unreliable. We evaluated a device for nonvoluntary force assessment. METHODS We tested 8 patients (unknown myopathy n = 2, inflammatory myopathy, facioscapulohumeral muscular dystrophy, mitochondrial myopathy, dysferlinopathy, multi-minicore disease, Becker-Kiener muscular dystrophy, n = 1 each). Isometric twitch torques of ankle dorsiflexors were measured after fibular nerve stimulation. RESULTS Six patients had decreased torques vs. 8 controls (men: median Newton-meter 1.6 vs. 5.7, women: 0.2 vs. 3.9, both P < 0.0001). Values correlated with Manual Muscle Test results (r = 0.73; r(2) = 0.53; P < 0.0001). In weak dorsiflexors, torque could be measured despite lower signal-to-noise ratios. In 2 patients with hypertrophy, we measured increased torques. CONCLUSIONS Nonvoluntary muscle force assessment can be used in patients with myopathies, and values correlate with voluntary forces determined by traditional methods. Muscle Nerve 53: 913-917, 2016. |
| Databáze: | OpenAIRE |
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