Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro
| Autor: | Alejandro M. Brunser, Verónica V. Olavarría, Arnold Hoppe, Violeta Díaz, Sergio Illanes, Pablo M. Lavados, Paula Muñoz |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Streptokinase Ischemia General Medicine Thrombolysis 030204 cardiovascular system & hematology medicine.disease Surgery Coronary arteries 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Thrombolytic drug Modified Rankin Scale medicine business Prospective cohort study Stroke 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Revista médica de Chile. 144:1266-1269 |
| ISSN: | 0034-9887 |
| DOI: | 10.4067/s0034-98872016001000005 |
| Popis: | Background: The effectiveness of intravenous thrombolysis (IVT) in cerebral ischemia is time dependent. Stroke mimics (SM) are frequent in emergency rooms. The effort to reduce door to needle time, can lead to administer thrombolytics to SM. Aim: To describe the frequency and prognosis of SM treated with IVT. Material and methods: Prospective analysis of all patients evaluated in a Chilean private clinic between December 2004 and July 2015 with a suspected acute ischemic stroke (AIS). We calculated the number of SM that were treated with IVT. In these patients, we analyzed the presence of symptomatic cerebral hemorrhage defined as the presence of a neurological deterioration of four points or more on the National Institute of Health Stroke Scale, the presence of extracranial bleeding according to Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries criteria and the patient's functional status at three months by modified Rankin scale (MRS). Results: We evaluated 1417 patients with suspected AIS, of which 240 (16.9%) were finally diagnosed as SM. A total of 197 patients were treated with IVT, of these 10 (5%) corresponded to SM. All SM patients treated with thrombolytic drugs were functionally independent at 3 months and showed no bleeding complications. Conclusions: Occasionally SM patients were treated with IVT. This treatment was not associated with bleeding complications and the prognosis of these patients at three months was favorable. |
| Databáze: | OpenAIRE |
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