THE EFFECT OF HYSTERECTOMY UPON THE OVARY WITH REFERENCE TO A POSSIBLE HORMONAL ACTION OF THE ENDOMETRIUM UPON THE OVARY
| Autor: | Daniel R. Mishell, Leon Motyloff |
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| Rok vydání: | 1941 |
| Předmět: | |
| Zdroj: | Endocrinology. 28:436-440 |
| ISSN: | 1945-7170 0013-7227 |
| DOI: | 10.1210/endo-28-3-436 |
| Popis: | THE PROBLEM of the fate of the ovaries following hysterectomy is still underdiscussion. Many believe that the removal of the uterus initiates atrophic changes in theovaries with subsequent onset of menopausal symptoms. Others maintain that the uterus hasno direct influence upon ovarian function, and that whatever changes are brought about are subsequent either to mechanical trauma, or to interference with ovarian blood supply following operation. Early workers (1–5) established the fact that abnormal changes occur in the ovary of laboratory animals following hysterectomy. Others (6, 7, 8) attempted to prevent the development of such changes by transplantation of endometrial tissue. Within recent years the suggestion has appeared that the uterus elaborates a hormone with a definite action upon the ovary (9, 10). In an experimental study on rabbits, Sessums and Murphy (11) concludedthat a degenerative effect upon the ovaries is produced by removal of the uterus and thatautotransplantation of endometrial tis... |
| Databáze: | OpenAIRE |
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