New Injectable Bone Substitute Using Reversible Thermosensitive Hydrogel and BCP Granules: In Vivo Rabbit Experiments

Autor:	T. Le François, Xavier Bourges, Jean-Louis Rouvillain, Serge Baroth, P.A. Uzel, N. Bourgeois, Guy Daculsi
Rok vydání:	2008
Předmět:	Materials science Biocompatibility Mechanics of Materials In vivo Mechanical Engineering Composite number Injectable bone General Materials Science Rabbit (nuclear engineering) Bioceramic Poloxamer Bone ingrowth Biomedical engineering
Zdroj:	Key Engineering Materials. :457-460
ISSN:	1662-9795
DOI:	10.4028/www.scientific.net/kem.396-398.457
Popis:	We have developed a new injectable bone substitute combining specific granules of BCP with or without radiopaque elements with a reversible thermo sensitive resorbable carrier such as Pluronic F-127. The composite is liquid at ambient temperature and set as hydrogel at 37°C. Rabbit experiment demonstrates high biocompatibility and bone ingrowth at the expense of the injectable bioceramic composite.
Databáze:	OpenAIRE
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