Influence of therapy continuous positive airway pressure on arterial stiffness in patients with arterial hypertension and obstructive sleep apnea
| Autor: | O. O. Torbas, N. A. Krushynska, Yu. M. Sirenko, O. L. Rekovets |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Ukrainian Journal of Cardiology. 29:17-29 |
| ISSN: | 2664-4479 1608-635X |
| DOI: | 10.31928/2664-4479-2022.5-6.1729 |
| Popis: | The aim – to assess the arterial stiffness changes in patients with arterial hypertension (AH) and obstructive sleep apnea (OSA) and possibilities of its correction by continuous positive airway pressure (CPAP)-therapy.Materials and methods. 185 patients with mild and moderate AH (49.8±0.8 years old) were enrolled in the study and divided into groups: 1st group – patients who had OSA (n=148), 2nd group – patients without OSA (control group, n=37). They underwent clinical and special examination: unattended somnography by dual-channel portable monitor device, estimation of daily sleepiness by Epworth Sleepiness Scale, office and ambulatory blood pressure monitoring, echocardiography and applanation tonometry. In 10 months follow-up study were included 105 patients, who were divided into 4 subgroups: A – patients with moderate to severe OSA on CPAP (n=23); B – patients with moderate to severe OSA without CPAP (n=29); C – patients with mild OSA (n=29); D – patients without OSA (controls, n=24). All patients received similar antihypertensive therapy according to 2013 ESH/ESC Guidelines.Results and discussion. Patients with AH and OSA (mean apnea-hypopnea index (AHI) 38.10±2.51 event/h) in comparison with patients without OSA (mean AHI 3.02±0.25 event/h) had significantly higher body mass index (35.20±0.57 vs 30.60±0.79 kg/m, p |
| Databáze: | OpenAIRE |
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