Novel taxanes from the needles of Taxus canadensis

Autor:	Junzeng Zhang, Lolita O. Zamir, Orval A. Mamer, JianHui Wu, Francoise Sauriol
Rok vydání:	1999
Předmět:	chemistry.chemical_compound Natural product chemistry biology Organic Chemistry Drug Discovery Botany Taxus canadensis Nanotechnology biology.organism_classification Biochemistry
Zdroj:	Tetrahedron. 55:14323-14340
ISSN:	0040-4020
Popis:	Nineteen taxanes were characterized for the first time in the needles of the Canadian yew. Four of these metabolites are novel: taxinine-11, 12-oxide (1), 7-acetoxytaxuspine C (2), 5-cinnamoyltaxin B (3), and 7, 9-deacetyltaxinine B (4). Compound 1 is the second 11,12-epoxy-taxane known and 7-oxygenated-3, 11-cyclotaxane structures are unique to Taxus canadensis. In addition, taxinine and taxinine E were found to be major taxanes in the Canadian yew. The structures of all the taxanes were rigorously established by spectroscopic methods.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e47195a24fcdaf8c7dc4cfbdbb1d1aa1 https://doi.org/10.1016/s0040-4020(99)00930-8 Zobrazit plný text záznamu Full Text from ScienceDirect