Enantiomeric 2-anilino-2-oxo-1,3,2-oxazaphosphorinanes: Synthesis and NMR-investigation of their non-racemic mixtures

Autor:	Andrzej Okruszek, Andrei B. Ouryupin, Mikhail I. Kadyko, Ryszard Kinas, Wojciech J. Stec, Pavel V. Petrovskii, E. I. Fedin
Rok vydání:	1995
Předmět:	Inorganic Chemistry Diastereomeric recrystallization Stereochemistry Chemistry Organic Chemistry Diastereomer Organic chemistry Physical and Theoretical Chemistry Enantiomer Catalysis Equilibrium constant
Zdroj:	Tetrahedron: Asymmetry. 6:1813-1824
ISSN:	0957-4166
DOI:	10.1016/0957-4166(95)00227-g
Popis:	Enantiomeric R-(−)- and (S)-(+)-2-anilino-2-oxo-1,3,2-oxazaphosphorinanes ( 1 ) have been synthesized by catalytic debenzylation of separated diastereomers of 3-(α-methylbenzyl)-2-anilino-2-oxo-1,3,2-oxazaphosphorinanes. Self-induced diastereomeric anisochronicity in non-racemic mixtures of these enantiomers was shown to vary with enantiomeric composition, overall specimen concentration, and temperature. The equilibrium constants of monomer-dimer and homo-cross-associate diastereomeric equilibria are estimated for the first time.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e470ea76654e6a22abc39f780242e9c0 https://doi.org/10.1016/0957-4166(95)00227-g Zobrazit plný text záznamu Full Text from ScienceDirect