Lipase-mediated selective acetylation of primary alcohols in ethyl acetate

Autor:	Ernane C. de Souza, Moises Romero‐Ortega, Horacio F. Olivo
Rok vydání:	2018
Předmět:	Primary (chemistry) biology 010405 organic chemistry Organic Chemistry Ethyl acetate Primary alcohol 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound chemistry Acetylation Drug Discovery biology.protein Organic chemistry Phenols Lipase
Zdroj:	Tetrahedron Letters. 59:287-290
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2017.12.041
Popis:	An environmental friendly process to selectively acetylate primary alcohols was demonstrated. The esterification process consists of treatment of a primary alcohol in the presence of immobilized C. antarctica lipase (Novozyme-435) in ethyl acetate at room temperature. Primary alcohols were acetylated in the presence of secondary alcohols and phenols.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e45be364e65aff10d833c9cfca1f488e https://doi.org/10.1016/j.tetlet.2017.12.041 Zobrazit plný text záznamu Full Text from ScienceDirect