Long-term Cryopreserved Autologous Hematopoietic Stem Cells Following Azacytidine to Successfully Treat Severe Invasive Pulmonary Aspergillosis After Therapy-Related Myelodysplastic Syndrome and CD8+ T-cell Autoimmune Disorders: A Case Report
Autor: | A. Salemme, Fabrizio Pane, I. Cappuccio, M.G. Rascato, Novella Pugliese, Simona Avilia, Marco Picardi, Francesco Grimaldi, A. Severino, G. Cerciello, Claudia Giordano |
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Rok vydání: | 2021 |
Předmět: |
Oncology
Cancer Research medicine.medical_specialty medicine.medical_treatment Disease Cryopreservation 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases Internal medicine medicine Cytotoxic T cell Chemotherapy business.industry fungi food and beverages Hematology medicine.disease Lymphoma Radiation therapy Haematopoiesis 030220 oncology & carcinogenesis Stem cell business 030215 immunology |
Zdroj: | Clinical Lymphoma Myeloma and Leukemia. 21:e722-e725 |
ISSN: | 2152-2650 |
DOI: | 10.1016/j.clml.2021.05.008 |
Popis: | Clinical Practice Points • MDS can occur in patients who have a history of prior exposure to chemotherapy and/or radiotherapy for a previous lymphoma. • MDS can occur with autoimmune disorders not responsive to immunosuppressive treatments. • Cytopenias and immunosuppressive treatments can lead to infections from opportunistic agents. • Mobilizing more cells than the amount needed to be infused could save patients with haematological disease from later cytopenic conditions. |
Databáze: | OpenAIRE |
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