NZB cells actively interfere with the establishment of tolerance to BGG in radiation chimeras

Autor:	C A Laskin, P A Smathers, R Lieberman, A D Steinberg
Rok vydání:	1983
Předmět:	Immunology Immunology and Allergy
Zdroj:	The Journal of Immunology. 131:1121-1125
ISSN:	1550-6606 0022-1767
DOI:	10.4049/jimmunol.131.3.1121
Popis:	We report experiments designed to determine if the tolerance defect in NZB mice results from i) failure of NZB cells to become tolerant, or ii) the ability of NZB cells to interfere actively with the development of tolerance. The results indicate that NZB cells are primed by the tolerogen itself and actively interfere with the expression of tolerance by DBA/2 cells, which normally can be rendered tolerant.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e455c7075877de3f653fbcc46eefc378 https://doi.org/10.4049/jimmunol.131.3.1121 Zobrazit plný text záznamu