STELLATE NONHEREDITARY IDIOPATHIC FOVEOMACULAR RETINOSCHISIS: NOVEL FINDINGS AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY ANALYSIS
Autor: | Kathleen R Schildroth, Ian Holman, Jonathan S. Chang, Tyler Etheridge, Mihai Mititelu |
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Rok vydání: | 2023 |
Předmět: |
Multimodal imaging
medicine.medical_specialty genetic structures Peripheral retinoschisis business.industry Retinoschisis General Medicine medicine.disease Normal limit eye diseases Ophthalmology Oct angiography Dorzolamide Foveal medicine sense organs Intravitreal bevacizumab business medicine.drug |
Zdroj: | RETINAL Cases & Brief Reports. 17:165-169 |
ISSN: | 1935-1089 |
Popis: | Purpose To present novel findings in stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR), including the largest series of optical coherence tomography angiography (OCT-A) findings to date. Methods A retrospective case series with multimodal imaging was obtained and reviewed. Results All three patients were women, ages 59-63. Two cases were unilateral and one was bilateral. Vision ranged from 20/20 to 20/60 in the affected eyes. Peripheral retinoschisis was observed in all three patients. All patients were followed for a minimum of one year. In one case, progressive macular retinoschisis leading to foveal involvement was observed over two years, with an associated vision decline from 20/25 to 20/60. Attempted interventions included topical dorzolamide in all cases and intravitreal bevacizumab in one patient; however, no treatment effect was observed. Foveal avascular zone (FAZ) size was within normal limits (mean 280[micro]m). In all SNIFR eyes, the retinoschisis cavities were nonvascular. Conclusion Novel findings regarding SNIFR include the progressive nature of foveal involvement and the lack of response to topical dorzolamide and intravitreal bevacizumab. FAZ was normal in all eyes, consistent with the relatively preserved vision in these cases. Retinoschisis cavities were nonvascular in all eyes, a finding which may give insight into the mechanism of this disease. |
Databáze: | OpenAIRE |
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