ChemInform Abstract: Practical Synthesis of Functionalized 2-Thioxoimidazolidine Derivatives

Autor: Samia Bouzroura, Sophie Poulain, Fadila Balegroune, Lamouri Hammal, Bellara Nedjar-Kolli, Malika Hamadène
Rok vydání: 2008
Předmět:
Zdroj: ChemInform. 39
ISSN: 1522-2667
0931-7597
DOI: 10.1002/chin.200827129
Popis: High‐yielding syntheses of an unpublished series of 2‐thioxo‐imidazolidin‐4‐ones 6 bearing an N‐ethoxycarbonyl and amidyl moieties an N1 and C5, respectively, are reported. These derivatives were obtained by intramolecular cyclization of 3‐ethylhydrazinoacetate 3,4‐dihydro maleimides 4 in the presence of ethyl or phenylisothiocyanate 2 under neutral conditions.
Databáze: OpenAIRE