Popis: |
Diffusion MRI is a magnetic resonance imaging technique in which the contrast mechanism is determined by the microscopic mobility of water molecules. In vivo, tissue structures such as cell membranes impede the diffusive motion of water molecules, meaning tissue with dense cellularity can be distinguishable from tissue with less densely packed cells, or pure fluid. The motion sensitization in diffusion MRI has an orientational dependence, meaning the orientation of structures such as the white matter fasciculi can be inferred. Detailed analysis of the diffusion MRI signal can also allow for inference of information such as intra-axonal volume and axon diameter in neuronal tissue. Diffusion MRI therefore provides a unique window onto microstructural information in vivo. |